Hashimoto H, Tsugawa M, Nasu Y, Kumon H, Murata T, Takeda K, Irie S, Shirasaki Y, Akaeda T, Ohashi T, Kondo K, Takamoto H, Mizuno A, Kobuke M, Nishi M
Department of Urology, Okayama University School of Medicine.
Hinyokika Kiyo. 1999 Jun;45(6):397-401.
We compared the safety and efficacy of transurethral resection of the prostate (TURP) with a thick loop and with a standard loop. We compared 36 consecutive men (median age, 70 years) with symptomatic benign prostatic hyperlasia (BPH) treated by TURP with a thick loop to a cohort of 36 men (median age, 72 years) treated by TURP with a standard loop. The safety parameters of evaluation included the operative time, blood loss, chronological changes in serum sodium, and complications. The efficacy parameters of evaluation included International Prostate Symptom Score, quality of life assessment, peak urinary flow rate, and post-void residual urine volume. The operative time (median, 49.5 versus 43.5 minutes), blood loss (median, 179 versus 127 ml), and change in serum sodium (median, -4.0 versus -6.0 mEq/L) were not significantly greater in the thick loop group than in the standard loop group, respectively. There were no major complications in either group. Clinically significant improvement was observed in all efficacy parameters in both groups, with no difference between the two groups. These results suggest that TURP with a thick loop is not necessarily superior to TURP with a standard loop in terms of decreasing the blood loss and decreasing the operative time.
我们比较了使用粗环和标准环经尿道前列腺切除术(TURP)的安全性和有效性。我们将36例连续接受使用粗环TURP治疗的有症状良性前列腺增生(BPH)男性患者(中位年龄70岁)与36例接受使用标准环TURP治疗的男性患者(中位年龄72岁)进行了比较。评估的安全参数包括手术时间、失血量、血清钠的时间变化以及并发症。评估的有效性参数包括国际前列腺症状评分、生活质量评估、最大尿流率和排尿后残余尿量。粗环组的手术时间(中位数,49.5对43.5分钟)、失血量(中位数,179对127毫升)和血清钠变化(中位数,-4.0对-6.0毫当量/升)分别并不显著高于标准环组。两组均无重大并发症。两组在所有有效性参数方面均观察到临床上显著的改善,两组之间无差异。这些结果表明,就减少失血量和缩短手术时间而言,使用粗环的TURP不一定优于使用标准环的TURP。