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血管肉瘤:当前综述

Angiosarcoma: current review.

作者信息

Fedok F G, Levin R J, Maloney M E, Tipirneni K

机构信息

Department of Surgery, Section of Otolaryngology--Head and Neck Surgery, Penn State Geisinger Health System, The Milton S. Hershey Medical Center, Hershey, 17033-0850, USA.

出版信息

Am J Otolaryngol. 1999 Jul-Aug;20(4):223-31. doi: 10.1016/s0196-0709(99)90004-2.

Abstract

Angiosarcoma (AS) is a rare malignant tumor of the skin and soft tissues. Due to this lesions's histopathologic similarity to other soft tissue and skin neoplasms, several names had been previously used to describe AS. In the following article, we present a comprehensive review of the literature and prior studies pertaining to AS. The purpose of this article is to provide the reader with a better understanding of the causative factors, clinical findings, and histological features of this uncommon but potentially lethal tumor. Furthermore, we discuss present therapeutic options and outcomes as well as summarize recent advances in AS tumor biology and cytogenetics.

摘要

血管肉瘤(AS)是一种罕见的皮肤和软组织恶性肿瘤。由于这种病变在组织病理学上与其他软组织和皮肤肿瘤相似,以前曾使用过几个名称来描述AS。在以下文章中,我们对与AS相关的文献和先前研究进行了全面综述。本文的目的是让读者更好地了解这种不常见但可能致命的肿瘤的致病因素、临床发现和组织学特征。此外,我们讨论了目前的治疗选择和结果,并总结了AS肿瘤生物学和细胞遗传学的最新进展。

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