Katal Sanaz, Gholamrezanezhad Ali, Kessler Michael, Olyaei Mojtaba, Jadvar Hossein
Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Keck School of Medicine, University of Southern California (USC), 1520 San Pablo Street, Suite L1600, Los Angeles, CA 90033.
PET Clin. 2018 Oct;13(4):609-621. doi: 10.1016/j.cpet.2018.05.011.
Soft tissue sarcomas (STSs) account for less than 1% of adult solid tumors and about 7% of pediatric malignancies, causing 2% of cancer-related deaths. With the advent of PET-computed tomography (CT), the value of (18) fluorine-2-fluoro-2-deoxy-d-glucose (FDG) PET imaging to improve the management of STSs has been explored. FDG PET imaging has been found useful in restaging and treatment response assessment. This article reviews current knowledge and application of FDG PET-CT in initial diagnosis, staging, restaging, treatment response monitoring, and prognosis, with a brief overview of the most common histologic subtypes of STS.
软组织肉瘤（STSs）占成人实体瘤的比例不到1%，在儿童恶性肿瘤中约占7%，导致2%的癌症相关死亡。随着正电子发射断层扫描-计算机断层扫描（PET-CT）的出现，已对（18）氟-2-氟-2-脱氧-d-葡萄糖（FDG）PET成像在改善软组织肉瘤管理方面的价值进行了探索。已发现FDG PET成像在再分期和治疗反应评估中有用。本文回顾了FDG PET-CT在初始诊断、分期、再分期、治疗反应监测和预后方面的当前知识及应用，并简要概述了软组织肉瘤最常见的组织学亚型。
