Tkachev S I, Alieva S B, Alferov V S
N.N.Blokhin Center for Cancer Research, Russian Medical Academy, Moscow.
Vopr Onkol. 1999;45(3):305-8.
Two modalities of radiotherapy of locally advanced tumors (T3N0M0) of the larynx were compared in the treatment of 89 patients. Forty-six patients of group I received 2 Gy daily, 5 times a week (COD 65-70 Gy), while 43 patients of group 11--1.1 Gy of multifractionated radiation twice a day, at 4-hr interval (COD 70-75 Gy). Five-year survival in group 1 was 67.1--11%, recurrence-free rate--54 +/- 7.3%, while in group 11--76 +/- 6.5 and 67 +/- 7.1%, respectively, (p < 0.4).
对89例喉局部晚期肿瘤（T3N0M0）患者的两种放射治疗方式进行了比较。I组46例患者每天接受2戈瑞，每周5次（总剂量65 - 70戈瑞），而II组43例患者每天分两次接受1.1戈瑞的多分次放疗，间隔4小时（总剂量70 - 75戈瑞）。I组的5年生存率为67.1% - 11%，无复发生存率为54±7.3%，而II组分别为76±6.5%和67±7.1%，（p < 0.4）。
