Bräunig P, Krüger S, Shugar G
Klinik für Psychiatrie, Verhaltensmedizin und Psychosomatik, Klinikum Chemnitz, Akademisches Lehrkrankenhaus, Universität Leipzig.
Fortschr Neurol Psychiatr. 1999 Jul;67(7):306-17. doi: 10.1055/s-2007-994981.
The study investigates the prevalence, clinical characteristics and implications of catatonic symptoms in mania.
Sixty-one in patients with DSM-III-R bipolar disorder, manic or mixed episode established by SCID were assessed for the presence of catatonia by a 21-item rating scale. Associated symptoms, comorbidity and severity of the manic episode were also systematically assessed.
Nineteen patients fulfilled criteria for catatonic mania exhibiting between 5 and 16 catatonic symptoms. Catatonic manics had more mixed episodes, more severe manic symptoms, more general psychopathology, a higher prevalence of comorbidity, longer hospitalization and lower GAF-scores than the non-catatonics.
The results indicate that catatonic symptoms are a marker of a more severe course and outcome in mania.
本研究调查躁狂发作时紧张症症状的患病率、临床特征及影响。
采用21项评定量表，对61例经SCID确诊为DSM-III-R双相情感障碍、躁狂或混合发作的住院患者进行紧张症评估。同时系统评估相关症状、共病情况及躁狂发作的严重程度。
19例患者符合紧张性躁狂标准，表现出5至16种紧张症症状。与非紧张症患者相比，紧张性躁狂患者有更多的混合发作、更严重的躁狂症状、更普遍的精神病理学表现、更高的共病患病率、更长的住院时间及更低的大体功能评定量表（GAF）评分。
结果表明，紧张症症状是躁狂发作更严重病程及预后的一个标志。
