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Induction of DNA double-strand breaks by electroporation of restriction enzymes into mammalian cells.

作者信息

Carney J P, Morgan W F

机构信息

Department of Radiation Oncology, University of California, San Francisco, USA.

出版信息

Methods Mol Biol. 1999;113:465-71. doi: 10.1385/1-59259-675-4:465.

DOI:10.1385/1-59259-675-4:465
PMID:10443443
Abstract
摘要

相似文献

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Nuclear myosin/actin-motored contact between homologous chromosomes is initiated by ATM kinase and homology-directed repair proteins at double-strand DNA breaks to suppress chromosome rearrangements.同源染色体之间由核肌球蛋白/肌动蛋白驱动的接触由ATM激酶和双链DNA断裂处的同源性定向修复蛋白启动，以抑制染色体重排。
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Formation of carcinogenic chromosomal rearrangements in human thyroid cells after induction of double-strand DNA breaks by restriction endonucleases.限制酶诱导双链 DNA 断裂后人类甲状腺细胞中致癌染色体重排的形成。
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