Bettega G, Aitedajer T, Mole C, Bouchet P, Jacquemin P, Sanson P, Mallet J L, Stricker M, Gérard H
Service de Chirurgie Plastique et Maxillo-Faciale, Centre Hospitalier Universitaire de Grenoble.
Rev Stomatol Chir Maxillofac. 1999 Apr;100(1):6-12.
Three-dimensional reconstruction of histologic structures is still a real challenge. This is the reason why very few specimens are published, especially for the head.
The chondrocranium of an 18-mm human embryo was reconstructed from serial histologic sections. The three-dimensional reconstruction was based on a software used in geology and adapted to medical applications. This software was able to smooth the reconstructed model, i.e. to correct the distortions due to the histologic preparation.
The chondrocranium model is presented. To facilitate spatial orientation, we added the reconstruction of Merkel cartilage, of Reichert cartilage, of the vertebrae, and of the cerebrum. The different portions of the chondrocranium are described.
The three-dimensional result is described and advantageously compared to the rare wax models available. The morphological differences are detailed.
This technique of three-dimensional reconstruction with its smoothing procedure is a very well adapted method for reconstruction of histologic structures. The results presented confirm the educational value of this tool, which is otherwise a powerful instrument of morphogenic study.
组织学结构的三维重建仍然是一项真正的挑战。这就是已发表的标本非常少的原因，尤其是头部标本。
从连续组织学切片重建了一个18毫米人类胚胎的软骨颅。三维重建基于一款地质学中使用的软件，并针对医学应用进行了调整。该软件能够使重建模型平滑，即校正因组织学制备导致的变形。
展示了软骨颅模型。为便于空间定位，我们补充了梅克尔软骨、赖歇特软骨、椎骨和大脑部分的重建。描述了软骨颅的不同部分。
描述了三维结果，并与现有的罕见蜡模型进行了有益比较。详细阐述了形态学差异。
这种带有平滑程序的三维重建技术是一种非常适合重建组织学结构的方法。所呈现的结果证实了该工具的教育价值，否则它是形态发生学研究的有力工具。
