Wood D M, Plehwe W E, Colman P G
University of Bristol, UK.
Diabet Med. 1999 Jul;16(7):605-8. doi: 10.1046/j.1464-5491.1999.00101.x.
To document aspirin usage and the prevalence of large and small vessel complications in patients with diabetes mellitus (DM) attending the outpatient diabetes clinics of a large public hospital.
All patients attending diabetes outpatient clinics at The Royal Melbourne Hospital in Melbourne, Australia were surveyed over a 3-month period.
Complete data were available on 629 of 632 (296 male) patients surveyed. Of the 29.3% of patients who were suffering from one or more macrovascular complication (ischaemic heart disease, cerebrovascular disease or peripheral vascular disease), 63% were currently on aspirin treatment. Of those not on aspirin, 65% had no contra-indication to aspirin treatment and a further 19% had only a relative contra-indication of either aspirin or warfarin treatment recorded.
The published recommendations for the use of aspirin in patients with macrovascular disease were generally being followed in this clinic-based population. However, a significant proportion of patients without a contra-indication to treatment were still not receiving aspirin. The lack of clear evidence-based guidelines for aspirin use may be a factor in its under-prescription. This survey suggests clear evidence-based guidelines should be established and disseminated.
记录在一家大型公立医院门诊糖尿病诊所就诊的糖尿病患者阿司匹林的使用情况以及大血管和小血管并发症的患病率。
对澳大利亚墨尔本皇家墨尔本医院糖尿病门诊的所有患者进行了为期3个月的调查。
在632名(296名男性)接受调查的患者中,629名患者有完整数据。在患有一种或多种大血管并发症(缺血性心脏病、脑血管疾病或外周血管疾病)的患者中,29.3%的患者目前正在接受阿司匹林治疗。在未服用阿司匹林的患者中,65%没有阿司匹林治疗的禁忌证,另有19%仅记录有阿司匹林或华法林治疗的相对禁忌证。
在这个以诊所为基础的人群中,普遍遵循了已发表的关于大血管疾病患者使用阿司匹林的建议。然而,相当一部分没有治疗禁忌证的患者仍未接受阿司匹林治疗。缺乏明确的阿司匹林使用循证指南可能是其处方不足的一个因素。这项调查表明应制定并传播明确的循证指南。