Allan A, Andersen W, Rosenbaum M, Bhawan J
Department of Dermatology, Boston University School of Medicine, MA, USA.
Am J Dermatopathol. 1999 Aug;21(4):387-91. doi: 10.1097/00000372-199908000-00015.
A 76-year-old woman presented with a 7-mm, hard, pink nodule at the site of an appendectomy scar of more than 70 years' duration. The clinical impression at the time of biopsy was that of a keloid. Surprisingly, light microscopic examination revealed classic histologic features of late-stage lichen sclerosus et atrophicus (LSA) overlying a scar. Elastic tissue stain highlighted the unusual presence of abundant nodules of elastin in the reticular dermis only.
一名76岁女性,在阑尾切除术后超过70年的瘢痕部位出现一个7毫米大小、质地坚硬的粉红色结节。活检时的临床印象是瘢痕疙瘩。令人惊讶的是,光镜检查显示在瘢痕上方有晚期硬化萎缩性苔藓(LSA)的典型组织学特征。弹性组织染色仅突出显示网状真皮中存在大量异常的弹性蛋白结节。