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[肢端硬化萎缩性苔藓]

[Acral lichen sclerosus et atrophicus].

作者信息

Steff M, Toulemonde A, Croue A, Lemerle E, Le Corre Y, Verret J-L

机构信息

Service de dermatologie, CHU d'Angers, université d'Angers, 4, rue Larrey, 49933 Angers cedex 9, France.

出版信息

Ann Dermatol Venereol. 2008 Mar;135(3):201-4. doi: 10.1016/j.annder.2007.11.020. Epub 2008 Mar 4.

Abstract

BACKGROUND

Lichen sclerosus et atrophicus rarely affects the feet or hands and in this case, it is generally part of widespread cutaneous involvement. We report a case of lichen sclerosus et atrophicus involving only the extremities and the vulvar and perigenital area.

PATIENTS AND METHODS

A 56-year-old woman presented with lesions of the hands and feet, with ivory white papules on the dorsal aspect of the feet and the distal phalanx of the fingers, a few small keratotic papules with central depressions in the hollow of the palms, erythema on soles and thenar and hypothenar eminences. Further examination revealed lichen sclerosus et atrophicus of the vulva and genitocrural skinfolds. Histological study of these various cutaneous lesions yielded similar results and revealed the typical features of lichen sclerosus et atrophicus.

DISCUSSION

A few cases of lichen sclerosus et atrophicus confined to the hands and/or feet have been reported, involving the palms and soles or nail folds, but none has so far affected the genitalia. To our knowledge, no cases of lichen sclerosus et atrophicus involving both faces of the hands and feet and the genital region have ever been reported.

摘要

背景

硬化萎缩性苔藓很少累及手足,在此病例中,它通常是广泛皮肤受累的一部分。我们报告一例仅累及四肢及外阴和生殖器周围区域的硬化萎缩性苔藓病例。

患者与方法

一名56岁女性,手足出现皮损,足部背侧和手指远端指节有乳白色丘疹,手掌心有一些中央凹陷的小角化性丘疹,足底、大鱼际和小鱼际隆起处有红斑。进一步检查发现外阴及股股沟皮肤皱襞处有硬化萎缩性苔藓。对这些不同皮肤损害进行组织学研究,结果相似,均显示出硬化萎缩性苔藓的典型特征。

讨论

已有少数局限于手部和/或足部的硬化萎缩性苔藓病例报道,累及手掌、足底或甲襞,但迄今为止尚无累及生殖器的病例。据我们所知,从未有过硬化萎缩性苔藓同时累及手足两面及生殖器区域的病例报道。

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