Cui L, Kasegawa H, Murakami Y, Hanaki H, Hiramatsu K
Department of Bacteriology, Juntendo University, Tokyo, Japan.
Scand J Infect Dis. 1999;31(2):208-9. doi: 10.1080/003655499750006326.
We report on a rare fatal case of postoperative toxic shock syndrome caused by infection with a highly virulent methicillin-resistant Staphylococcus aureus strain, designated Sak-1, which was found to be characteristic in its increased production of toxic shock syndrome toxin 1 in human whole blood (about 30-fold more than produced in Tod Hewitt broth). The strain also produced a high level of toxic shock syndrome toxin 1 in the circulating blood of mice experimentally infected with the strain.
我们报告了一例罕见的致命性术后中毒性休克综合征病例，该病例由感染一种高毒力的耐甲氧西林金黄色葡萄球菌菌株（命名为Sak-1）引起，该菌株在人全血中产生中毒性休克综合征毒素1的量增加（比在托德-休伊特肉汤中产生的量多约30倍），这一特性十分典型。该菌株在实验感染小鼠的循环血液中也产生了高水平的中毒性休克综合征毒素1。
