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遗传性血色素沉着症和非肝硬化性肝脏患者的肝细胞癌。病例报告。

Hepatocellular carcinoma in a patient with hereditary hemochromatosis and noncirrhotic liver. A case report.

作者信息

Köhler H H, Höhler T, Küsel U, Kirkpatrick C J, Schirmacher P

机构信息

Institute of Pathology, Johannes-Gutenberg-University, Mainz, Germany.

出版信息

Pathol Res Pract. 1999;195(7):509-13. doi: 10.1016/S0344-0338(99)80055-7.

DOI:10.1016/S0344-0338(99)80055-7
PMID:10448668
Abstract

A case of a 62-year-old patient with hereditary hemochromatosis is reported, who developed hepatocellular carcinoma (HCC) in the absence of cirrhosis and other potential risk factors for HCC. Occurrence of HCC in patients with genetic hemochromatosis and noncirrhotic liver is a rare event which has previously been described only six times and appears to be limited to male patients.

摘要

报告了一例62岁遗传性血色素沉着症患者,该患者在无肝硬化及其他肝细胞癌潜在危险因素的情况下发生了肝细胞癌。遗传性血色素沉着症且无肝硬化的患者发生肝细胞癌是一种罕见事件,此前仅报道过6次,且似乎仅限于男性患者。

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Hepatocellular carcinoma in a patient with hereditary hemochromatosis and noncirrhotic liver. A case report.遗传性血色素沉着症和非肝硬化性肝脏患者的肝细胞癌。病例报告。
Pathol Res Pract. 1999;195(7):509-13. doi: 10.1016/S0344-0338(99)80055-7.
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Hepatocellular carcinoma in a noncirrhotic patient with hereditary hemochromatosis.一名患有遗传性血色素沉着症的非肝硬化患者发生肝细胞癌。
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引用本文的文献

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Hereditary hemochromatosis: Temporal trends, sociodemographic characteristics, and independent risk factor of hepatocellular cancer - nationwide population-based study.遗传性血色素沉着症:时间趋势、社会人口学特征及肝细胞癌的独立危险因素——基于全国人群的研究
World J Hepatol. 2022 Sep 27;14(9):1804-1816. doi: 10.4254/wjh.v14.i9.1804.
2
Regression of Hepatic Fibrosis and Evolution of Cirrhosis: A Concise Review.肝纤维化的消退和肝硬化的演变:简要综述。
Adv Anat Pathol. 2021 Nov 1;28(6):408-414. doi: 10.1097/PAP.0000000000000312.
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Hepatocellular carcinoma in non-cirrhotic liver: A comprehensive review.
非肝硬化肝脏中的肝细胞癌:全面综述
World J Hepatol. 2019 Jan 27;11(1):1-18. doi: 10.4254/wjh.v11.i1.1.
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MicroRNAs and liver cancer associated with iron overload: therapeutic targets unravelled.微小 RNA 与铁过载相关的肝癌:治疗靶点的揭示。
World J Gastroenterol. 2013 Aug 28;19(32):5212-26. doi: 10.3748/wjg.v19.i32.5212.