Budenz D L, Chen P P, Weaver Y K
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Fla 33138, USA.
Arch Ophthalmol. 1999 Aug;117(8):1014-9. doi: 10.1001/archopht.117.8.1014.
To determine the indications and outcome of conjunctival advancement surgery for late-onset filtering bleb leaks.
Retrospective medical record review of a consecutive case series of all patients who underwent conjunctival advancement surgery for persistent late-onset glaucoma filtering bleb leaks at a tertiary referral center between December 1, 1985, and April 30, 1997.
Indications for surgery, preoperative and postoperative intraocular pressure (IOP), visual acuity, status of bleb leak, and need for reinstitution of medical therapy or reoperation for glaucoma.
Twenty-six eyes of 26 patients were analyzed. Complications from bleb leaks that necessitated surgical intervention included chronic ocular hypotony (n = 21), decreased visual acuity (n = 9), bleb-related infection (n = 11), hypotony maculopathy (n = 4), corneal edema with folds (n = 7), choroidal effusion (n = 3), and persistent shallow anterior chamber (n = 3). The mean +/- SD preoperative IOP was 5.7 +/- 4.9 mm Hg (range, 0-16 mm Hg). After a follow-up of 19.6 +/- 22.6 months, the IOP was 14.2 +/- 4.1 mm Hg for patients taking 1.1 +/- 1.3 glaucoma medications (all data given as mean +/- SD). Twelve patients (46%) had early-onset bleb leaks after revision, of which 7 (27%) closed spontaneously and 5 (19%) required resuturing. Two patients (8%) had a persistent bleb leak throughout the follow-up period. Thirteen patients (50%) required reinstitution of medical therapy during the follow-up period, and 2 (8%) required a reoperation for glaucoma for uncontrolled IOP.
Conjunctival advancement is a successful procedure for closing late-onset filtering bleb leaks. Some patients require suturing in the early postoperative period, but most patients eventually obtain permanent closure of the leak. Patients should be counseled of the possibility of requiring medical or surgical intervention for IOP control after revision.
确定结膜推进术治疗迟发性滤过泡渗漏的适应证及疗效。
回顾性分析1985年12月1日至1997年4月30日在一家三级转诊中心因持续性迟发性青光眼滤过泡渗漏而接受结膜推进术的所有患者的连续病例系列的病历。
手术适应证、术前及术后眼压(IOP)、视力、滤过泡渗漏情况,以及青光眼再次药物治疗或再次手术的必要性。
分析了26例患者的26只眼。需要手术干预的滤过泡渗漏并发症包括慢性低眼压(n = 21)、视力下降(n = 9)、滤过泡相关感染(n = 11)、低眼压性黄斑病变(n = 4)、角膜水肿伴褶皱(n = 7)、脉络膜脱离(n = 3)和持续性浅前房(n = 3)。术前平均±标准差眼压为5.7±4.9 mmHg(范围,0 - 16 mmHg)。随访19.6±22.6个月后,使用1.1±1.3种青光眼药物治疗的患者眼压为14.2±4.1 mmHg(所有数据均以平均±标准差表示)。12例患者(46%)在修复后出现早期滤过泡渗漏,其中7例(27%)自行闭合,5例(19%)需要再次缝合。2例患者(8%)在整个随访期间滤过泡持续渗漏。13例患者(50%)在随访期间需要重新开始药物治疗,2例患者(8%)因眼压控制不佳需要再次行青光眼手术。
结膜推进术是闭合迟发性滤过泡渗漏的一种成功方法。一些患者在术后早期需要缝合,但大多数患者最终能实现渗漏的永久性闭合。应告知患者修复后可能需要进行药物或手术干预以控制眼压。