Kosmin A S, Wishart P K
Glaucoma Clinic, St Paul's Eye Unit, Royal Liverpool University Hospital, United Kingdom.
Ophthalmic Surg Lasers. 1997 Jun;28(6):461-8.
Late bleb leak may follow months to years after filtration surgery. This article describes the surgical repair of eight leaking blebs using a full-thickness scleral graft and analyzes the efficacy of the procedure and its effect on intraocular pressure (IOP) control.
The indications for surgical bleb revision were hypotony maculopathy (2 eyes), endophthalmitis (2 eyes), bleb infection (2 eyes), and chronic epiphora and blurring of vision (2 eyes). All eyes were treated surgically through bleb excision and repair of the scleral defect with a full-thickness scleral graft. Conjunctival closure was performed either by its advancement to the limbus or by free conjunctival autograft. Follow-up ranged from 4 months to 7 years.
Surgery stopped the leak in all cases, and hypotony was relieved without loss of long-term IOP control. However, early postoperative IOP rises (> 30 mm Hg) occurred in 2 eyes and a pressure-lowering medication was necessary to achieve long-term IOP control (IOP < 22 mm Hg) in 3 eyes.
The technique described is an effective procedure for the treatment of late bleb leaks and is especially useful for the treatment of leaks found in association with full-thickness scleral defects. IOP spikes in the early postoperative period may occur, but long-term IOP control can be expected without the need for further filtration surgery.
滤过性手术后数月至数年可能出现迟发性滤过泡渗漏。本文描述了使用全层巩膜移植片对8个渗漏滤过泡进行手术修复,并分析了该手术的疗效及其对眼压(IOP)控制的影响。
手术修复滤过泡的指征为低眼压性黄斑病变(2只眼)、眼内炎(2只眼)、滤过泡感染(2只眼)以及慢性溢泪和视力模糊(2只眼)。所有患眼均通过切除滤过泡并用全层巩膜移植片修复巩膜缺损进行手术治疗。结膜闭合采用推进至角膜缘或游离结膜自体移植的方法。随访时间为4个月至7年。
手术在所有病例中均止住了渗漏,低眼压得到缓解,且未丧失长期眼压控制效果。然而,2只眼术后早期眼压升高(>30 mmHg),3只眼需要使用降眼压药物来实现长期眼压控制(眼压<22 mmHg)。
所描述的技术是治疗迟发性滤过泡渗漏的有效方法,尤其适用于与全层巩膜缺损相关的渗漏治疗。术后早期可能出现眼压峰值,但无需进一步的滤过性手术即可实现长期眼压控制。