Mellström A, Hartmann M, Jedlinska B, Jönsson K
Department of Anesthesiology, University Hospital, Malmö, Sweden.
Eur Surg Res. 1999;31(4):333-9. doi: 10.1159/000008710.
The effect of different fractions of inspired oxygen on subcutaneous oxygen tension, carbon dioxide tension and pH in relation to arterial and mixed venous blood gases and pH and hemodynamic variables was evaluated in 13 domestic pigs. Subcutaneous, arterial and mixed venous oxygen tensions were closely correlated (r = 0.94). A minor significant increase in subcutaneous carbon dioxide tension was noted during hyperoxia (p < 0.05). A major increase (33%) was noted during the last step of hypoxia, when arterial and mixed venous carbon dioxide tensions increased only 12 and 17%, respectively. A minor decrease in subcutaneous pH was noted during hyperoxia (p < 0.05) and a major decrease during hypoxia (p < 0.05). Measurements of subcutaneous tissue gases and pH are indicators of oxygen utilization during hyper- and hypoxia.
在13头家猪身上评估了不同吸氧分数对皮下氧分压、二氧化碳分压和pH值的影响，以及这些指标与动脉血和混合静脉血气、pH值及血流动力学变量之间的关系。皮下、动脉和混合静脉氧分压密切相关（r = 0.94）。高氧期间皮下二氧化碳分压有轻微显著升高（p < 0.05）。在缺氧的最后阶段，皮下二氧化碳分压大幅升高（33%），而此时动脉血和混合静脉血二氧化碳分压仅分别升高12%和17%。高氧期间皮下pH值有轻微下降（p < 0.05），缺氧期间则大幅下降（p < 0.05）。皮下组织气体和pH值的测量是高氧和缺氧期间氧利用情况的指标。
