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[抗结核药物治疗期间脑结核的矛盾性扩张性病变]

[Paradoxical expansive lesions of cerebral tuberculosis during antitubercular drug therapy].

作者信息

Andrade Filho A de S, Gomes A G, De Lemos A C, Neves M C, Souza Y M, Pereira S L, De Souza A P, Dos Santos P L

机构信息

Hospital Otávio Mangabeira/Secretaria da Saúde do Estado da Bahia, Departamento de Neuropsiquiatria (DNP) da Faculdade de Medicina (FAMED) da Universidade Federal da Bahia (UFBA), Brasil.

出版信息

Arq Neuropsiquiatr. 1999 Jun;57(2B):471-5. doi: 10.1590/s0004-282x1999000300020.

Abstract

Central nervous system involvement by tuberculosis presents two main types: tuberculosis meningitis or tuberculoma. This second condition has nowadays ideal conditions for development. We report three patients who developed paradoxical brain tuberculosis expansive lesion during the use of tuberculostatic drugs. The cases point out the importance of tomography follow up of patients who present neurological signs in the course of treatment for tuberculosis. The first two patients presented onset of the a neurological symptoms, associated with lung tuberculosis. The third patient previously had tuberculous meningitis. Computerized tomography was used to follow up these patients. Tuberculostatic and corticoid drugs were used for treatment.

摘要

结核病累及中枢神经系统主要有两种类型

结核性脑膜炎或结核瘤。如今,第二种情况具备了理想的发病条件。我们报告了3例在使用抗结核药物期间发生矛盾性脑结核扩展性病变的患者。这些病例指出了对在结核病治疗过程中出现神经症状的患者进行断层扫描随访的重要性。前两名患者出现神经症状,同时伴有肺结核。第三名患者曾患结核性脑膜炎。使用计算机断层扫描对这些患者进行随访。使用抗结核药物和皮质类固醇药物进行治疗。

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