Leenstra T S, Kuijpers-Jagtman A M, Maltha J C
Department of Orthodontics and Oral Biology, University of Nijmegen, The Netherlands.
Scand J Plast Reconstr Surg Hand Surg. 1999 Jun;33(2):169-76. doi: 10.1080/02844319950159415.
The aim of this study was to evaluate wound healing clinically and histologically in beagle dogs after palatal repair during growth by the partially split flap technique and the von Langenbeck technique. A standardised soft tissue defect was created in the medial region of the palate. The partially split flap technique was performed in 14 dogs (age 12 weeks). Von Langenbeck repair was simulated in 12 dogs (age 12 weeks). Four dogs (age 12 weeks) served as controls. Standardised slides of the palate were taken on eight occasions and the wound surface areas were measured. Histological sections were prepared at three different ages. The animals were studied until the age of 25 weeks. Re-epithelialisation was complete in roughly two weeks in dogs after palatal repair by the partially split flap technique. The histological features of this group were close to normal limits. After the von Langenbeck's procedure re-epithelialisation took about three weeks and scar tissue was firmly attached to bundle bone by Sharpey's fibres. We conclude that the histological appearance of the palatal tissues in dogs after palatal repair during growth by the partially split flap technique was close to normal. We assume that this is reason for more favourable dentoalveolar development after the partially split flap technique compared with von Langenbeck's repair.
本研究的目的是通过部分裂开瓣技术和冯·兰根贝克技术，在生长期间对比格犬进行腭裂修复后，从临床和组织学方面评估伤口愈合情况。在硬腭内侧区域制造一个标准化的软组织缺损。对14只犬（12周龄）实施部分裂开瓣技术。对12只犬（12周龄）模拟冯·兰根贝克修复术。4只犬（12周龄）作为对照。在八个时间点采集硬腭的标准化切片并测量伤口表面积。在三个不同年龄制备组织学切片。对这些动物进行研究直至25周龄。采用部分裂开瓣技术修复腭裂后的犬，大约两周内再上皮化完成。该组的组织学特征接近正常范围。在冯·兰根贝克手术之后，再上皮化约需三周时间，瘢痕组织通过夏皮氏纤维牢固附着于束状骨。我们得出结论，在生长期间采用部分裂开瓣技术修复腭裂后，犬硬腭组织的组织学外观接近正常。我们推测，这就是与冯·兰根贝克修复术相比，部分裂开瓣技术后牙槽骨发育更有利的原因。
