Positron emission tomography in juvenile Alexander disease.
作者信息
Sawaishi Y, Hatazawa J, Ochi N, Hirono H, Yano T, Watanabe Y, Okudera T, Takada G
机构信息
Department of Pediatrics, Akita University School of Medicine, Japan.
出版信息
J Neurol Sci. 1999 Jun 1;165(2):116-20. doi: 10.1016/s0022-510x(99)00090-8.
Abstract
A 13-year-old boy with cervical kyphosis was diagnosed as having juvenile Alexander disease because of the typical MRI findings, abnormally elevated alphaB-crystallin and heat shock protein 27 in the cerebrospinal fluid. Positron emission tomography with 18F-fluorodeoxyglucose demonstrated hypometabolism in the frontal white matter corresponding to the areas with leukodystrophy. However, the overlying gray matter preserved normal glucose metabolism.
摘要
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