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超排卵制剂对绵羊中脑、垂体和松果体中儿茶酚胺水平的影响。

The influence of superovulation preparations on the levels of catecholamines in eminentia mediana, the pituitary and pineal gland of the sheep.

作者信息

Pástorová B

机构信息

Department of Normal Physiology, University of Veterinary Medicine, Kosice, Slovak Republic.

出版信息

Physiol Res. 1998;47(6):471-5.

PMID:10453755
Abstract

The influence of hormonal superovulation preparations of FSH (450 IU) or PMSG (1500 IU), on the levels of catecholamines (dopamine, norepinephrine and epinephrine) was studied in the oestrus period using radioenzymatic methods. The administration of FSH caused a significant increase in the concentrations of norepinephrine (NE) and epinephrine (EPI) in eminentia mediana (EM) of sheep (p<0.001 and p<0.01, respectively). The pituitary gland exhibited an increase in the level of norepinephrine after administration PMSG while no marked changes were recorded for epinephrine and dopamine (DA). The administration of FSH affected the increase in pituitary epinephrine (p<0.01). The hormonal stimulation by FSH resulted in a marked decrease of dopamine (p<0.05) as well as in a significant increase of norepinephrine (p<0.05) and epinephrine (p<0.05) in the epiphysis. The comparison of the effect of hormonal preparations on the changes in catecholamine levels showed that the effect of FSH was observed mostly in eminentia mediana and the pituitary gland while that of PMSG was recorded in the epiphysis.

摘要

采用放射酶法研究了促卵泡素(FSH,450IU)或孕马血清促性腺激素(PMSG,1500IU)的激素超排制剂对发情期儿茶酚胺(多巴胺、去甲肾上腺素和肾上腺素)水平的影响。给绵羊注射FSH后,其正中隆起(EM)中的去甲肾上腺素(NE)和肾上腺素(EPI)浓度显著升高(分别为p<0.001和p<0.01)。注射PMSG后,垂体中的去甲肾上腺素水平升高,而肾上腺素和多巴胺(DA)未见明显变化。注射FSH影响垂体肾上腺素水平升高(p<0.01)。FSH的激素刺激导致松果体中多巴胺显著降低(p<0.05),去甲肾上腺素(p<0.05)和肾上腺素(p<0.05)显著升高。激素制剂对儿茶酚胺水平变化影响的比较表明,FSH的作用主要在正中隆起和垂体中观察到,而PMSG的作用则在松果体中记录到。

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