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大发作诱发的高尿酸血症。

Grand mal-provoked hyperuricemia.

作者信息

Lühdorf K, Petersson H, Pedersen K

出版信息

Acta Neurol Scand. 1978 Nov;58(5):280-7. doi: 10.1111/j.1600-0404.1978.tb02888.x.

DOI:10.1111/j.1600-0404.1978.tb02888.x
PMID:104541
Abstract

A significant increase in S-urate was found postictally in 17 patients with two or more grand mal seizures within 24 h. In six patients S-urate was above the level at which hyperuricemic renal failure may develop. Impaired renal function was observed in two patients who had extremely high S-urates. It is proposed that prophylactic procedures against hyperuricemic renal failure should be carried out in all patients with repetitive convulsions.

摘要

在24小时内发生两次或更多次癫痫大发作的17例患者中,发作后发现血清尿酸盐(S-urate)显著升高。6例患者的S-urate高于可能发生高尿酸血症性肾衰竭的水平。在S-urate极高的2例患者中观察到肾功能受损。建议对所有反复惊厥的患者采取预防高尿酸血症性肾衰竭的措施。

相似文献

1
Grand mal-provoked hyperuricemia.大发作诱发的高尿酸血症。
Acta Neurol Scand. 1978 Nov;58(5):280-7. doi: 10.1111/j.1600-0404.1978.tb02888.x.
2
Hyperuricaemic acute renal failure after epileptic seizures.癫痫发作后高尿酸血症性急性肾衰竭
Lancet. 1975 Aug 30;2(7931):385-7. doi: 10.1016/s0140-6736(75)92897-4.
3
[Grand mal-hyperuricemia--and acute nephropathy].[癫痫大发作 - 高尿酸血症 - 与急性肾病]
Ugeskr Laeger. 1977 Nov 21;139(47):2818-20.
4
Case report: rhabdomyolysis following grand mal seizures presenting as a delayed and increasingly dense nephrogram.病例报告:癫痫大发作后横纹肌溶解症表现为延迟且密度逐渐增加的肾图。
Clin Radiol. 1993 Feb;47(2):139-40. doi: 10.1016/s0009-9260(05)81192-4.
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Reddish-orange discoloration of urine due to uric acid crystalluria after recurrent seizures.反复癫痫发作后因尿酸结晶尿导致尿液呈红橙色变色。
Kidney Int. 2012 Jun;81(12):1281. doi: 10.1038/ki.2012.61.
6
[Investigation of etiologies for acute renal failure due to rhabdomyolysis in 5 patients].5例横纹肌溶解症所致急性肾衰竭的病因调查
Nihon Jinzo Gakkai Shi. 1990 Nov;32(11):1221-7.
7
[Mangiferin promotes uric acid excretion and kidney function improvement and modulates related renal transporters in hyperuricemic mice].[芒果苷促进高尿酸血症小鼠尿酸排泄、改善肾功能并调节相关肾转运蛋白]
Yao Xue Xue Bao. 2010 Oct;45(10):1239-46.
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Taurine decreased uric acid levels in hyperuricemic rats and alleviated kidney injury.牛磺酸降低了高尿酸血症大鼠的尿酸水平,并减轻了肾脏损伤。
Biochem Biophys Res Commun. 2017 Jul 29;489(3):312-318. doi: 10.1016/j.bbrc.2017.05.139. Epub 2017 May 25.
9
Immediate transition from a petit mal absence into a grand mal seizure. Case report.
Eur Neurol. 1976;14(1):11-6. doi: 10.1159/000114721.
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Total saponins from Discorea nipponica ameliorate urate excretion in hyperuricemic mice.穿龙薯蓣总皂苷改善高尿酸血症小鼠的尿酸排泄。
Planta Med. 2014 Oct;80(15):1259-68. doi: 10.1055/s-0034-1383048. Epub 2014 Sep 23.

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A Patient with Acute Kidney Injury Associated with Massive Proteinuria and Acute Hyperuricemia after Epileptic Seizures.癫痫发作后伴大量蛋白尿和急性高尿酸血症的急性肾损伤患者。
Intern Med. 2022 Nov 15;61(22):3401-3408. doi: 10.2169/internalmedicine.8808-21. Epub 2022 Apr 23.
2
Acute metabolic effects of tonic-clonic seizures.强直阵挛性发作的急性代谢效应。
Epilepsia Open. 2019 Oct 22;4(4):599-608. doi: 10.1002/epi4.12364. eCollection 2019 Dec.
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Acute Uric Acid Nephropathy following Epileptic Seizures: Case Report and Review.
癫痫发作后急性尿酸肾病:病例报告与文献复习
Case Rep Nephrol. 2019 Feb 4;2019:4890287. doi: 10.1155/2019/4890287. eCollection 2019.
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Laboratory markers of cardiac and metabolic complications after generalized tonic-clonic seizures.全身强直阵挛性发作后心脏和代谢并发症的实验室指标。
BMC Neurol. 2017 Sep 19;17(1):187. doi: 10.1186/s12883-017-0965-4.
5
Acute Renal Failure with Severe Loin Pain and Patchy Renal Vasoconstriction in a Patient without Hypouricemia, Provoked by Epileptic Seizure.癫痫发作诱发的无低尿酸血症患者的急性肾衰竭伴严重腰痛及散在性肾血管收缩
Intern Med. 2017;56(15):2001-2005. doi: 10.2169/internalmedicine.56.8328. Epub 2017 Aug 1.
6
Acute renal failure, hyperuricaemia, and myoglobinuria.急性肾衰竭、高尿酸血症和肌红蛋白尿。
Br Med J. 1979 May 12;1(6173):1233-4. doi: 10.1136/bmj.1.6173.1233-a.