Lühdorf K, Petersson H, Pedersen K
Acta Neurol Scand. 1978 Nov;58(5):280-7. doi: 10.1111/j.1600-0404.1978.tb02888.x.
A significant increase in S-urate was found postictally in 17 patients with two or more grand mal seizures within 24 h. In six patients S-urate was above the level at which hyperuricemic renal failure may develop. Impaired renal function was observed in two patients who had extremely high S-urates. It is proposed that prophylactic procedures against hyperuricemic renal failure should be carried out in all patients with repetitive convulsions.
在24小时内发生两次或更多次癫痫大发作的17例患者中,发作后发现血清尿酸盐(S-urate)显著升高。6例患者的S-urate高于可能发生高尿酸血症性肾衰竭的水平。在S-urate极高的2例患者中观察到肾功能受损。建议对所有反复惊厥的患者采取预防高尿酸血症性肾衰竭的措施。