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腹主动脉瘤的风险权衡。最好在择期手术而非急诊手术中进行修复。

Weighing risks in abdominal aortic aneurysm. Best repaired in an elective, not an emergency, procedure.

作者信息

Gorski Y, Ricotta J J

机构信息

Department of Surgery, State University of New York at Stony Brook, Health Science Center School of Medicine 11794-8430, USA.

出版信息

Postgrad Med. 1999 Aug;106(2):69-70, 75-80. doi: 10.3810/pgm.1999.08.651.

Abstract

Abdominal aortic aneurysms are believed to result from several factors, one probably being inflammation that leads to dilatation, plaque deposition, and degeneration of the arterial wall. Most of these aneurysms are asymptomatic, but abdominal or back pain, shock, and a pulsatile abdominal mass indicate rupture. Initial aneurysm size exceeding 5 cm (2 in.) in diameter and the presence of hypertension and COPD are important predictors of rupture. The overall operative mortality rate with elective repair of an abdominal aortic aneurysm has been reported to range from 0.9% to 5% at university medical centers, and it is only slightly higher at community hospitals. However, with a ruptured aneurysm and emergency repair, the mortality rate rises to about 75%. Several long-term studies using life-table methods have found that 5-year survival rates after aneurysm repair range from 49% to 84%. This rate is significantly better than the 5-year survival rate of patients who did not have an abdominal aortic aneurysm repaired. However, it is not as good as that of the normal age-matched population, probably because many patients with an aneurysm have concomitant coronary artery disease.

摘要

腹主动脉瘤被认为是由多种因素导致的,其中一个因素可能是炎症,炎症会导致动脉壁扩张、斑块沉积和变性。这些动脉瘤大多无症状,但腹痛、背痛、休克和腹部搏动性肿块提示动脉瘤破裂。初始动脉瘤直径超过5厘米(2英寸)以及存在高血压和慢性阻塞性肺疾病是破裂的重要预测因素。据报道,在大学医学中心,择期修复腹主动脉瘤的总体手术死亡率在0.9%至5%之间,在社区医院仅略高。然而,对于破裂的动脉瘤进行急诊修复时,死亡率会升至约75%。几项使用生命表方法的长期研究发现,动脉瘤修复后的5年生存率在49%至84%之间。这一比率明显优于未进行腹主动脉瘤修复的患者的5年生存率。然而,它不如年龄匹配的正常人群,这可能是因为许多动脉瘤患者同时患有冠状动脉疾病。

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