一头日本黑牛的多囊性肾发育异常

Multicystic renal dysplasia in a Japanese black bull.

作者信息

Ushigaki K, Uchida K, Murakami T, Yamaguchi R, Tateyama S

机构信息

Department of Veterinary Pathology, Faculty of Agriculture, Miyazaki University, Japan.

出版信息

J Vet Med Sci. 1999 Jul;61(7):839-42. doi: 10.1292/jvms.61.839.

DOI:10.1292/jvms.61.839

PMID:10458111

Abstract

Multicystic renal dysplasia was found in a 6-day-old Japanese black bull. Grossly, both kidneys were markedly small (2.0 x 3.5 cm) with numerous cysts ranging from 1 to 8 mm in diameter. Histopathologically, both kidneys consisted of many irregularly enlarged cysts, immature glomeruli, small ducts and anomalous stromal connective tissues containing focal persistent mesenchyme characterized by a proliferation of stellate cells with myxomatous area. These features are compatible with those of multicystic renal dysplasia in humans and other mammals.

摘要

在一头6日龄的日本黑公牛身上发现了多囊性肾发育不良。大体上，双侧肾脏明显缩小（2.0×3.5厘米），有许多直径从1至8毫米不等的囊肿。组织病理学检查显示，双侧肾脏由许多不规则增大的囊肿、未成熟的肾小球、小导管以及含有局灶性持续间充质的异常间质结缔组织组成，该间充质以星状细胞增生伴黏液瘤样区域为特征。这些特征与人类和其他哺乳动物的多囊性肾发育不良特征相符。