通过荧光原位杂交技术对15号染色体与Y染色体易位进行产前确认。
Prenatal confirmation of the translocation between chromosome 15 and Y-chromosome by fluorescence in situ hybridization.
作者信息
Fukada Y, Yasumizu T, Amemiya A, Kohno K, Takizawa M, Hoshi K
机构信息
Department of Obstetrics and Gynecology, Yamanashi Medical University, Nakakoma-gun, Japan.
出版信息
Tohoku J Exp Med. 1999 Mar;187(3):285-9. doi: 10.1620/tjem.187.285.
A 30-year-old woman and her husband visited our hospital with habitual abortion as the complaint. Chromosome examination revealed a normal 46, XX for her and 46, XY, 15, der (15) t (Y; 15) (q12; p12) for him. After her pregnancy amniocentesis was performed. The karyotype was 46, XX, 15, der (15) t (Y; 15) (q12; p12) pat. ish der (15) (DYZ1+). A female baby was delivered. The growth of the baby was normal at 12 months of age.
一名30岁女性及其丈夫因习惯性流产前来我院就诊。染色体检查显示，她的染色体核型正常，为46, XX，而她丈夫的染色体核型为46, XY, 15, der (15) t (Y; 15) (q12; p12)。她怀孕后进行了羊水穿刺。核型为46, XX, 15, der (15) t (Y; 15) (q12; p12) pat. ish der (15) (DYZ1+)。产下一名女婴。该婴儿12个月大时生长发育正常。
Zotero 插件