Hussell T, Openshaw P
Department of Respiratory Medicine, Imperial College School of Science, Technology and Medicine, National Heart and Lung Institute at St Mary's, Norfolk Place, London, W2 1PG, UK.
Curr Opin Microbiol. 1999 Aug;2(4):410-4. doi: 10.1016/S1369-5274(99)80072-1.
Respiratory syncytial virus (RSV) is the major cause of infantile bronchiolitis, and is an important pathogen in the elderly and in the developing world. The production of full length cDNA clones now allows precise genetic engineering of RSV, while knowledge of the immunopathogenesis of augmented disease gives hope that effective vaccines will soon be developed.
