Korabiowska M, Brinck U, Ruschenburg I, Dengler H, Droese M, Berger H
Department of Cytopathology, Georg-August University, Göttingen, Germany.
In Vivo. 1999 May-Jun;13(3):251-4.
The significant difference of DNA mismatch repair genes expression between naevi and melanomas was demonstrated by our research group in the previous study. The main aim of this study was to compare the expression of MLH1, MSH2, PMS1 and PMS2 in 31 naevus cell naevi, 12 fibromatous naevi and 30 dysplastic naevi. The expression of DNA mismatch repair proteins was found in all naevi investigated. However, the expression (percentage of positively stained cells) was significantly higher in naevus cell naevi than in dysplastic and fibromatous ones.
