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严重脓毒症和脓毒性休克的诊断与管理

The diagnosis and management of severe sepsis and septic shock.

作者信息

Wilson R F

出版信息

Heart Lung. 1976 May-Jun;5(3):422-9.

PMID:1046050
Abstract

Shock due to or associated with sepsis may present a clinical picture quite different from that usually seen in hypovolemic or cardiogenic shock. Any trend which suggests increasing sepsis should be treated aggressively as if shock were present. The earlier such therapy is begun, the better the results tend to be. Perhaps the greatest errors in the therapy of severe sepsis and septic shock are (1) delayed control of the primary septic process, (2) giving too little fluid in the early phases of therapy (and too much later), and (3) delaying ventilator assistance if the patient's ventilation or blood gases are deteriorating.

摘要

由脓毒症引起或与之相关的休克,其临床表现可能与通常所见的低血容量性或心源性休克截然不同。任何提示脓毒症加重的趋势都应积极治疗,就如同休克已经存在一样。这种治疗开始得越早,效果往往越好。在严重脓毒症和脓毒性休克的治疗中,最大的错误可能是:(1)对原发性脓毒症过程的控制延迟;(2)在治疗早期补液过少(而在后期过多);(3)如果患者的通气或血气状况恶化,延迟给予机械通气支持。

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