Domzał T M
Kliniki Neurochirurgicznej Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej w Warszawie.
Neurol Neurochir Pol. 1999 Mar-Apr;33(2):351-7.
64 cases with spasmodic torticollis were observed during 5 years and treated with botulinum toxin (BTX). BTX was injected into dystonic muscles mostly into sternocleidomastoid then--trapezius, and splenius capitis muscle. Improvement (excellent, good and fair) was achieved in 40 patients (62%). Lack of information about 6 patient (9%). Injections were repeated every 3-4 months and in several cases even 1-2 during the year. After several injections atrophy and denervation potentials in EMG were observed in the majority of injected muscles. Neurotic syndromes coexisting with dystonia had worsening influence on therapeutic effects. Adverse events were observed in 5 cases. Treatment with BTX is very simple, easy, harmless and can be administered in outpatients.
在5年期间观察了64例痉挛性斜颈患者，并用肉毒杆菌毒素（BTX）进行治疗。BTX被注射到张力障碍肌肉中，主要是胸锁乳突肌，然后是斜方肌和头夹肌。40例患者（62%）病情得到改善（优、良、中）。6例患者（9%）信息缺失。每3 - 4个月重复注射，在一些病例中甚至一年注射1 - 2次。多次注射后，在大多数注射肌肉中观察到肌电图显示萎缩和失神经电位。与肌张力障碍共存的神经症综合征对治疗效果有不良影响。5例出现不良事件。BTX治疗非常简单、易行、无害，可在门诊进行。
