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Clinical remission of xeroderma pigmentosum-associated squamous cell carcinoma with isotretinoin and chemotherapy: case report.

作者信息

Saade M, Debahy N E, Houjeily S

机构信息

Division of Hematology-Oncology, Lebanese University Medical School, Beirut.

出版信息

J Chemother. 1999 Aug;11(4):313-7. doi: 10.1179/joc.1999.11.4.313.

DOI:10.1179/joc.1999.11.4.313
PMID:10465136
Abstract

We report the case of a 7-year old boy with xeroderma pigmentosum and a large squamous cell carcinoma of the cheek. He received a combination of isotretinoin (1 mg/kg/day) and chemotherapy for a period of 3 months and showed complete remission of the tumor. Treatment modalities of malignancies in xeroderma pigmentosum are reviewed and discussed in relation to the literature. The advantages of our protocol were emphasized because of the rapid improvement in a short time with minimal side effects.

摘要

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