Fitkin J, Ho G T
Mount Carmel Health System, Columbus, Ohio 43222, USA.
Am Fam Physician. 1999 Aug;60(2):549-52, 554.
Peyronie's disease is an acquired inflammatory condition of the penis associated with penile curvature and,in some cases, pain. It primarily affects men between 45 and 60 years of age, although an age range of 18 to 80 years has been reported. If left untreated, Peyronie's disease may cause fibrotic, nonexpansile thickening of relatively discrete areas of the corpora tunica, typically resulting in focal bend, pain or other functional or structural abnormalities of the erect penis. Many cases resolve without treatment. Medical therapies, including antioxidants (such as vitamin E and potassium aminobenzoate) and corticosteroids injected directly into the plaque, lack adequate scientific support. Surgery remains a mainstay when conservative measures fail.
佩罗尼氏病是一种后天性阴茎炎症性疾病，伴有阴茎弯曲，在某些情况下还会引起疼痛。它主要影响45至60岁的男性，不过也有报道称发病年龄范围在18至80岁之间。如果不进行治疗，佩罗尼氏病可能会导致白膜相对离散区域出现纤维化、无扩张性增厚，通常会导致勃起阴茎出现局部弯曲、疼痛或其他功能或结构异常。许多病例不经治疗即可自愈。包括抗氧化剂（如维生素E和氨基苯甲酸酯钾）和直接注射到斑块内的皮质类固醇在内的药物治疗缺乏充分的科学依据。当保守治疗措施失败时，手术仍是主要的治疗手段。
