Cowie F, Jones R
Beatson Oncology Centre, Western Infirmary, Glasgow, UK.
Clin Oncol (R Coll Radiol). 1999;11(3):196-7. doi: 10.1053/clon.1999.9042.
Adjuvant radiotherapy to the breast or chest wall is given to some patients with breast cancer, to reduce the risk of local recurrence. It is known to be associated with various late sequelae, including subcutaneous fibrosis, telangiectasia and pulmonary fibrosis. Delivering radiotherapy to the chest wall and nodal drainage areas presents the technical problem of matching the glancing and anterior supraclavicular fields. Overlap between these fields will result in underlying tissues receiving a larger dose than intended; similarly, a gap results in an inadequate dose. We present the case history of a patient with subcutaneous calcification occurring as a late sequela of radiotherapy to the chest wall and anterior supraclavicular field. This has not been previously reported and is thought to have arisen from a high dose region in an area of overlap between fields.
一些乳腺癌患者会接受乳房或胸壁的辅助放疗，以降低局部复发风险。已知其与多种晚期后遗症相关，包括皮下纤维化、毛细血管扩张和肺纤维化。对胸壁和淋巴结引流区域进行放疗存在技术难题，即如何匹配切线野和前锁骨上野。这些野之间的重叠会导致深层组织接受的剂量超过预期；同样，存在间隙则会导致剂量不足。我们介绍了一名患者的病例史，该患者胸壁和前锁骨上野放疗的晚期后遗症为皮下钙化。此前尚无相关报道，据认为这是由野之间重叠区域的高剂量区所致。
