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[三环类抗抑郁药自杀性中毒]

[Suicidal poisoning with tricyclic antidepressants].

作者信息

Chodorowski Z, Anand J S

机构信息

I Kliniki Chorób Wewnetrznych, Chorób Wewnetrznych Akademii Medyczne w Gdansku.

出版信息

Przegl Lek. 1999;56(6):438-41.

Abstract

In the period from 1989 to 1998, 98 patients with suicidal tricyclic antidepressants poisoning were treated, including 47 men and 51 women from 16 to 74 (mean 35) years old. Thirty persons were poisoned by tricyclic antidepressants, in 68 remaining cases intoxications were mixed eg. including tricyclic antidepressants and benzodiazepines, phenothiazines, barbiturates, alcohol, amizepine, salicylates. The main causes of suicides were various kinds of depression (66%) as well as psychopathy and sociopathy (18%). Twenty patients attempted repeatedly to commit suicide. These were mainly patients suffering from endogenous depression, psychopathy and schizophrenia. In the examined group five patients died (5%) but three women out of them were aged, suffered from congestive heart failure and were poisoned with tricyclic antidepressants, benzodiazepines and barbiturates.

摘要

1989年至1998年期间,对98例三环类抗抑郁药自杀中毒患者进行了治疗,其中男性47例,女性51例,年龄在16至74岁(平均35岁)之间。30人因三环类抗抑郁药中毒,其余68例为混合中毒,例如包括三环类抗抑郁药与苯二氮䓬类、吩噻嗪类、巴比妥类、酒精、阿米替林、水杨酸盐。自杀的主要原因是各种抑郁症(66%)以及精神变态和反社会人格障碍(18%)。20例患者多次企图自杀。这些主要是患有内源性抑郁症、精神变态和精神分裂症的患者。在所检查的组中有5例患者死亡(5%),但其中3名女性年事已高,患有充血性心力衰竭,且因三环类抗抑郁药、苯二氮䓬类和巴比妥类中毒。

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