Crockarell J R, Berry D J, Lewallen D G
Department of Orthopedics, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Bone Joint Surg Am. 1999 Aug;81(8):1073-9. doi: 10.2106/00004623-199908000-00003.
Nonunion after a periprosthetic femoral fracture associated with total hip arthroplasty occurs rarely. There is little information, to our knowledge, regarding the prevalence of this complication, its treatment, and the functional outcomes of treatment. The purpose of this study was to identify the patterns and frequency of nonunions of femoral fractures around total hip prostheses and to evaluate the results and problems associated with treatment of this complication in a consecutive series of patients.
The study included twenty-three nonunions of periprosthetic femoral fractures in twenty-three patients with an average age of fifty-five years (range, twenty-two to eighty-five years) at the time of the initiation of treatment of the nonunion. Thirteen of the fractures occurred during or after a primary total hip arthroplasty, and ten occurred during or after a revision total hip arthroplasty. According to the classification system of Duncan and Masri, there were six B1 fractures (associated with a well fixed prosthesis), seven B2 fractures (associated with a loose stem), and ten B3 fractures (associated with very poor proximal bone). Ten patients were managed with revision to a long-stem prosthesis. Six patients had revision to a proximal femoral replacement prosthesis. A two-stage technique consisting of removal of the prosthesis and open reduction and internal fixation of the nonunion followed by reimplantation of the prosthesis was used in two patients. Two patients were managed initially with bone-grafting alone, and two patients were managed nonoperatively. One patient who had an infection at the site of the nonunion was managed definitively with resection arthroplasty.
The duration of clinical follow-up averaged 8.3 years (range, three months to twenty-three years), and that of radiographic surveillance averaged 7.0 years (range, eight months to seventeen years). Of the thirteen patients in whom an attempt to achieve union was made and for whom radiographs were available, nine eventually had bone-healing. Five of the twenty-three femora became infected and were treated with resection arthroplasty. Of the seventeen patients who had not had a resection arthroplasty for infection and for whom radiographs were available at the time of the most recent follow-up, eleven had a stable and well fixed implant and six had a loose implant as seen radiographically or had had a revision because of aseptic loosening. Seventeen patients had no or mild pain at the time of the most recent follow-up, but ten required two-handed support to walk. The overall complication rate was 52 percent (twelve of twenty-three patients).
Nonunion of a femoral fracture associated with a total hip prosthesis is an infrequent problem. Treatment is difficult, with a high rate of complications and relatively poor functional outcomes. The data from this series must be interpreted with caution, as patients were managed over a period of three decades and many did not have the advantage of modern techniques of revision hip arthroplasty. Prevention of nonunion by optimum treatment of the initial fracture is most important. Treatment of a femoral nonunion about a total hip implant should be implemented on the basis of the status of the fixation of the prosthesis and the quality of the surrounding bone.
全髋关节置换术后假体周围股骨骨折不愈合的情况很少见。据我们所知,关于这种并发症的发生率、治疗方法及其治疗后的功能结果,相关信息较少。本研究的目的是确定全髋关节假体周围股骨骨折不愈合的模式和频率,并评估一系列连续患者中这种并发症的治疗结果及相关问题。
本研究纳入了23例假体周围股骨骨折不愈合患者,这些患者在开始治疗不愈合时的平均年龄为55岁(范围为22至85岁)。其中13例骨折发生在初次全髋关节置换术中或术后,10例发生在翻修全髋关节置换术中或术后。根据Duncan和Masri的分类系统,有6例B1型骨折(与假体固定良好相关),7例B2型骨折(与柄松动相关),10例B3型骨折(与近端骨质非常差相关)。10例患者接受了长柄假体翻修。6例患者接受了股骨近端置换假体翻修。2例患者采用了两阶段技术,即先取出假体,对不愈合部位进行切开复位内固定,然后再植入假体。2例患者最初仅接受了植骨治疗,2例患者接受了非手术治疗。1例在不愈合部位发生感染的患者最终接受了关节切除成形术。
临床随访时间平均为8.3年(范围为3个月至23年),影像学监测时间平均为7.0年(范围为8个月至17年)。在13例试图实现骨折愈合且有X线片的患者中,9例最终实现了骨愈合。23个股骨中有5例发生感染并接受了关节切除成形术。在17例未因感染接受关节切除成形术且在最近一次随访时有X线片的患者中,11例植入物稳定且固定良好,6例在X线片上显示植入物松动或因无菌性松动接受了翻修。17例患者在最近一次随访时无疼痛或仅有轻微疼痛,但10例患者行走时需要双手支撑。总体并发症发生率为52%(23例患者中的12例)。
全髋关节假体相关的股骨骨折不愈合是一个罕见问题。治疗困难,并发症发生率高,功能结果相对较差。由于这些患者的治疗跨越了三十年,且许多患者没有现代髋关节翻修技术的优势,因此本系列数据必须谨慎解读。通过对初始骨折进行最佳治疗来预防不愈合最为重要。全髋关节植入物周围股骨不愈合的治疗应根据假体的固定状态和周围骨质质量来实施。