天疱疮和大疱性类天疱疮。
Pemphigus and bullous pemphigoid.
作者信息
Nousari H C, Anhalt G J
机构信息
Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, MD 21205-2196, USA.
出版信息
Lancet. 1999 Aug 21;354(9179):667-72. doi: 10.1016/S0140-6736(99)03007-X.
Abstract
Pemphigus and bullous pemphigoid are distinct autoimmune blistering diseases that are characterised by the presence of autoantibodies directed against specific adhesion molecules of the skin and mucous membranes. The comparison and contrast of molecular mechanism of blister formation of these two diseases provide a rational diagnostic and therapeutic approach to affected patients.
摘要
天疱疮和大疱性类天疱疮是两种不同的自身免疫性水疱病，其特征是存在针对皮肤和黏膜特定黏附分子的自身抗体。对这两种疾病水疱形成分子机制的比较和对比，为受影响患者提供了合理的诊断和治疗方法。
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