Asami K, Yamaguchi T
Institute for Chemical Research, Kyoto University, Uji, Japan.
Ann Biomed Eng. 1999 Jul-Aug;27(4):427-35. doi: 10.1114/1.190.
The electrical and morphological properties of human erythrocytes under high hydrostatic pressure up to 500 MPa have been studied by dielectric spectroscopy. The pressure-induced changes in the dielectric behavior of erythrocyte suspensions indicate that hydrostatic pressure causes the change in cell shape from discoidal to spherical and hemolysis at 200-300 MPa, the formation of buds and spicular processes followed by vesiculation at 300-400 MPa, and the increase in the membrane capacitance at 400-500 MPa.
