Taylor S S
School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, Manchester, M13 9PT, UK.
Curr Biol. 1999;9(15):R562-4. doi: 10.1016/s0960-9822(99)80355-8.
A mitotic checkpoint arrests cell cycle progression in response to spindle damage. It now appears that this checkpoint has two separate arms, one that prevents anaphase and a second that prevents cytokinesis and DNA re-replication.
有丝分裂检查点会响应纺锤体损伤而阻止细胞周期进程。现在看来,这个检查点有两条独立的途径,一条阻止后期,另一条阻止胞质分裂和DNA再复制。