发育进化：昆虫的轴向模式形成

Developmental evolution: Axial patterning in insects.

作者信息

Dearden P, Akam M

机构信息

University Museum of Zoology, Department of Zoology, Downing Street, Cambridge, CB2 3EJ, UK.

出版信息

Curr Biol. 1999 Aug 26;9(16):R591-4. doi: 10.1016/s0960-9822(99)80381-9.

DOI:10.1016/s0960-9822(99)80381-9

PMID:10469587

Abstract

The Drosophila bicoid gene is well known for encoding a protein that forms a morphogenetic gradient with a key role in anterior patterning of the fruitfly embryo. Recent results suggest the evolution of bicoid might have involved dramatic changes in function - essentially the invention of a new regulatory protein.

摘要

果蝇的双胸基因因编码一种蛋白质而闻名，该蛋白质形成一种形态发生梯度，在果蝇胚胎的前部模式形成中起关键作用。最近的研究结果表明，双胸基因的进化可能涉及功能上的巨大变化——本质上是一种新的调控蛋白的诞生。