Todros T, Carmazzi C M, Bontempo S, Gaglioti P, Donvito V, Massobrio M
Department of Gynecology and Obstetrics, University of Turin, Italy.
Hum Reprod. 1999 Sep;14(9):2245-8. doi: 10.1093/humrep/14.9.2245.
This report describes a case of spontaneous ovarian hyperstimulation syndrome (OHSS) occurring in a pregnant woman carrying the factor V Leiden mutation. Even though prophylactic treatment for thrombo-embolism was adopted by administering low molecular weight heparin, the pregnancy was complicated by thromboses of the left subclavian, axillary, humeral and internal jugular veins during the second trimester of gestation. The pregnancy was managed conservatively and a healthy newborn was delivered at term. In order to avoid unnecessary laparotomy, we emphasize the importance of careful diagnosis in order to differentiate spontaneous OHSS from ovarian carcinoma, as well as the necessity to look for the presence of coagulation disorders in women affected by OHSS.
本报告描述了一例携带因子V莱顿突变的孕妇发生自发性卵巢过度刺激综合征（OHSS）的病例。尽管通过给予低分子量肝素对血栓栓塞进行了预防性治疗，但在妊娠中期，该孕妇仍并发了左锁骨下静脉、腋静脉、肱静脉和颈内静脉血栓形成。该妊娠采用保守治疗，足月时分娩出一名健康新生儿。为避免不必要的剖腹手术，我们强调仔细诊断以鉴别自发性OHSS与卵巢癌的重要性，以及在OHSS患者中寻找凝血障碍存在情况的必要性。
