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[大量消化道出血揭示的胃粒细胞肉瘤]

[Gastric granulocytic sarcoma revealed by a massive digestive hemorrhage].

作者信息

D'Alteroche L, Mor C, Durand V, De Muret A, Benbouker L, Colombat P, Danquechin Dorval E

机构信息

Service d'Hépato-Gastroentérologie, CHU Trousseau, Tours.

出版信息

Gastroenterol Clin Biol. 1999 Jun-Jul;23(6-7):779-82.

Abstract

We report the case of a 37-year-old-man having a chronic myelogenous leukemia, who presented, one month after a splenic acutization, massive gastrointestinal bleeding from ulcerated nodules of the gastric fundus. The histologic examination of one of these nodules showed granulocytic sarcoma. In spite of an endoscopic treatment by sclerotherapy with adrenalined serum, the death occurred during a hemorrhagic recurrence. This observation, which is the third case reported of gastric granulocytic sarcoma during the acutization of a myelogenous chronic leukemia, and the first revealed by fatal gastrointestinal bleeding, shows the particular gravity of gastrointestinal bleeding complicating granulocytic sarcoma.

摘要

我们报告了一例37岁慢性粒细胞白血病男性患者的病例,该患者在脾脏急性病变一个月后,出现胃底溃疡结节导致的大量胃肠道出血。对其中一个结节进行组织学检查显示为粒细胞肉瘤。尽管采用肾上腺素血清硬化疗法进行了内镜治疗,但患者在出血复发期间死亡。该病例是慢性粒细胞白血病急性病变期间报告的第三例胃粒细胞肉瘤病例,也是首例因致命性胃肠道出血而发现的病例,显示了粒细胞肉瘤并发胃肠道出血的严重性。

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