Ohno Y, Kawai M, Wakahara Y, Kitagawa T, Kakihara M, Arii Y
Department of Obstetrics and Gynecology, Toyohashi Municipal Hospital, Japan.
Obstet Gynecol. 1999 Sep;94(3):361-3. doi: 10.1016/s0029-7844(99)00294-x.
To compare ophthalmic arterial velocimetry in normotensive and preeclamptic gravidas with and without photophobia.
Ophthalmic arteries were studied by color-flow Doppler ultrasonography in 118 normotensive pregnant women, 20 gravidas with preeclampsia and no visual symptoms, and 11 with preeclampsia, photophobia, and retinal edema.
The ophthalmic arterial pulsatility index (PI) correlated negatively with gestational age (y = -0.01x + 1.84, r = -0.41, P<.01). Pulsatility index in preeclamptics with photophobia (0.71+/-0.17) was lowest among the three groups (P<.01) and was highest in normotensive pregnant women (1.41+/-0.21, P<.01). Mean velocity in normotensive pregnant women (0.19+/-0.05 m/second) was highest among the groups (P<.01) and was not significantly different in preeclamptic women with no visual symptoms (0.27+/-0.03 m/second) and with photophobia (0.30+/-0.02 m/second).
Preeclamptic women, especially those with photophobia, have orbital vascular vasodilation or hyperperfusion, or both.
比较有畏光和无畏光的正常血压及先兆子痫孕妇的眼动脉血流速度测定结果。
采用彩色多普勒超声对118例正常血压孕妇、20例无视觉症状的先兆子痫孕妇及11例有畏光和视网膜水肿的先兆子痫孕妇进行眼动脉研究。
眼动脉搏动指数（PI）与孕周呈负相关（y = -0.01x + 1.84，r = -0.41，P<0.01）。有畏光的先兆子痫患者的搏动指数（0.71±0.17）在三组中最低（P<0.01），而在正常血压孕妇中最高（1.41±0.21，P<0.01）。正常血压孕妇的平均速度（0.19±0.05米/秒）在各组中最高（P<0.01），无视觉症状的先兆子痫患者（0.27±0.03米/秒）和有畏光的先兆子痫患者（0.30±0.02米/秒）之间无显著差异。
先兆子痫患者，尤其是有畏光症状的患者，存在眼眶血管舒张或血流灌注过多，或两者皆有。
