Poliakova G A, Kazantseva I A, Kalinin A P, Perov A I, Bokova E V
M. V. Vladimirsky Moscow Regional Research Clinical Institute, Moscow.
Arkh Patol. 1999 May-Jun;61(3):30-4.
A comparative study of the mitotic index (MI) and karyometric indices in 15 adrenocortical tumors with clinical syndrome of hypercorticism allowed to distinguish between adenomas and carcinomas. Carcinomas with hypercorticoidism symptoms have common features with inactive carcinomas but are different by lower expression of malignancy criteria (polymorphism, atypia, necrotic foci, capsule and vessel invasion), higher MI, increasing deficiency of cell division and larger nuclear size of tumor cells. Such tumors may be included into the prognostic group of risk.
对15例伴有皮质醇增多临床综合征的肾上腺皮质肿瘤的有丝分裂指数（MI）和核测量指数进行比较研究，有助于区分腺瘤和癌。具有皮质醇增多症状的癌与无活性癌有共同特征，但在恶性标准（多形性、异型性、坏死灶、包膜和血管侵犯）的表达较低、MI较高、细胞分裂缺陷增加以及肿瘤细胞核尺寸较大方面存在差异。这类肿瘤可能属于预后风险组。
