Friedrich Y, Raniel Y, Lubovsky E, Friedman Z
Annette & Aron Rozin Department of Ophthalmology, Bnai-Zion Medical Center, Faculty of Medicine, Haifa, Israel.
J Cataract Refract Surg. 1999 Sep;25(9):1220-5. doi: 10.1016/s0886-3350(99)00157-1.
To determine the incidence of late inflammatory membrane formation with pigment precipitates on foldable silicone or poly(methyl methacrylate) (PMMA) intraocular lenses (IOLs) after phacoemulsification with or without simultaneous trabeculectomy and to identify probable causative factors.
Eye Department, Bnai-Zion Medical Center, and the Faculty of Medicine, the Technion, Haifa, Israel.
In this retrospective study, 155 eyes (140 patients) were divided into 4 groups by the surgery performed: Group 1, phacoemulsification combined with trabeculectomy and foldable silicone IOL implantation (12 eyes); Group 2, phacoemulsification combined with trabeculectomy and PMMA IOL implantation (15 eyes); Group 3, phacoemulsification alone with foldable silicone IOL implantation (66 eyes); Group 4, phacoemulsification alone with PMMA IOL implantation (62 eyes). Preoperative, intraoperative, and postoperative data were compared.
Late inflammatory membranes were found on the anterior surface of 33% of the IOLs in Group 1, 3% in Group 3, and none in Groups 2 and 4. Membranes developed 3 to 4 months after surgery, were resistant to topical corticosteroid treatment and required repeated neodymium:YAG laser treatments. No correlation with preoperative, intraoperative, or postoperative factors was found.
Foldable silicone IOLs may induce late postoperative inflammatory membranes with pigment precipitates, especially after combined phacoemulsification and trabeculectomy.
确定在有或没有同时进行小梁切除术的白内障超声乳化术后，可折叠硅胶或聚甲基丙烯酸甲酯（PMMA）人工晶状体（IOL）上出现伴有色素沉着的晚期炎症膜的发生率，并确定可能的致病因素。
以色列海法市巴伊兰医疗中心眼科和以色列理工学院医学院。
在这项回顾性研究中，155只眼（140例患者）根据所进行的手术分为4组：第1组，白内障超声乳化联合小梁切除术及植入可折叠硅胶人工晶状体（12只眼）；第2组，白内障超声乳化联合小梁切除术及植入PMMA人工晶状体（15只眼）；第3组，单纯白内障超声乳化并植入可折叠硅胶人工晶状体（66只眼）；第4组，单纯白内障超声乳化并植入PMMA人工晶状体（62只眼）。对术前、术中和术后数据进行比较。
第1组33%的人工晶状体前表面发现有晚期炎症膜，第3组为3%，第2组和第4组未发现。这些膜在术后3至4个月形成，对局部皮质类固醇治疗有抵抗，需要多次钕：钇铝石榴石激光治疗。未发现与术前、术中和术后因素相关。
可折叠硅胶人工晶状体可能会诱发伴有色素沉着的术后晚期炎症膜，尤其是在白内障超声乳化联合小梁切除术后。
