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The oropharyngeal delivery of interferons: where are we and where do we need to go?

作者信息

Bocci V

机构信息

Institute of General Physiology, University of Siena, Italy.

出版信息

J Interferon Cytokine Res. 1999 Aug;19(8):859-61. doi: 10.1089/107999099313361.

DOI:10.1089/107999099313361
PMID:10476929
Abstract

The controversial concept of oral delivery of interferon (IFN) is reviewed in relation to possible mechanisms of action. Although there is a rational basis and some positive clinical results for believing that it may work, problems remain to understand which is the most effective IFN preparation and why. Owing to a minimal cost and lack of toxicity, the oral as well as other unconventional routes of IFN delivery deserve to be evaluated because they may become useful.

摘要

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