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南澳大利亚州老年人群样本中口干症和唾液腺功能减退的发生率。

The occurrence of xerostomia and salivary gland hypofunction in a population-based sample of older South Australians.

作者信息

Thomson W M, Chalmers J M, Spencer A J, Ketabi M

机构信息

Department of Dental Public Health, University of Otago School of Dentistry, Dunedin, New Zealand.

出版信息

Spec Care Dentist. 1999 Jan-Feb;19(1):20-3. doi: 10.1111/j.1754-4505.1999.tb01363.x.

Abstract

This paper examines the prevalence of and concurrence between the symptoms of dry mouth (xerostomia) and reduced salivary flow (SGH) among a population-based sample of older South Australians. Participants in a longitudinal dental study of older people were asked a global question about their experience of dry mouth ("How often does your mouth feel dry?"), and those who responded "Always" or "Frequently" were categorized as xerostomic. Unstimulated whole salivary flow rate was measured, and individuals whose flow rate was less than 0.1 mL/min were categorized as SGH cases. Saliva samples were collected from 700 individuals, of whom 683 (97.7%) answered the dry-mouth question. The mean unstimulated salivary flow rate was 0.27 mL/min (SD 0.22). The prevalence of SGH was 22.1%, and the prevalence of xerostomia was 20.5%, but only 5.7% of participants had both conditions. Almost two-thirds of the sample had neither condition. Males and females differed in the degree of concurrence between the two conditions. It appears that, in the group studied, xerostomia and SGH were largely discrete conditions, supporting the assertion by other workers that low salivary flow may not be the key factor in the etiology of xerostomia among older people.

摘要

本文调查了南澳大利亚老年人群体样本中口干(口腔干燥症)症状与唾液分泌减少(SGH)之间的患病率及并发情况。在一项针对老年人的纵向牙科研究中,参与者被问及一个关于口干经历的总体问题(“您的口腔感觉干燥的频率如何?”),回答“总是”或“经常”的人被归类为口腔干燥症患者。测量了非刺激性全唾液流速,流速低于0.1 mL/分钟的个体被归类为SGH病例。从700名个体中采集了唾液样本,其中683人(97.7%)回答了口干问题。非刺激性唾液平均流速为0.27 mL/分钟(标准差0.22)。SGH的患病率为22.1%,口腔干燥症的患病率为20.5%,但只有5.7%的参与者同时患有这两种疾病。几乎三分之二的样本没有这两种疾病。男性和女性在这两种疾病的并发程度上存在差异。在研究的群体中,口腔干燥症和SGH似乎在很大程度上是独立的疾病,这支持了其他研究人员的观点,即唾液流速降低可能不是老年人口腔干燥症病因的关键因素。

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