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一种使用可吸收肺动脉环扎带治疗婴儿主动脉缩窄合并室间隔缺损的手术新策略。

A new strategy for the surgical treatment of aortic coarctation associated with ventricular septal defect in infants using an absorbable pulmonary artery band.

作者信息

Bonnet D, Patkaï J, Tamisier D, Kachaner J, Vouhé P, Sidi D

机构信息

Service de Cardiologie Pédiatrique, Hôpital Necker-Enfants Malades, Paris, France.

出版信息

J Am Coll Cardiol. 1999 Sep;34(3):866-70. doi: 10.1016/s0735-1097(99)00268-5.

Abstract

OBJECTIVES

We propose a new strategy using coarctation repair together with a polidioxanone absorbable pulmonary artery banding to limit operative risk and to spare infants with aortic coarctation subsequent operations.

BACKGROUND

The alternative for the surgical management of aortic coarctation associated with ventricular septal defect (VSD) is single-stage repair versus coarctation repair with or without banding of the pulmonary artery.

METHODS

Eleven infants (mean weight 2,560 +/- 1,750 g, range 1,320 to 3,800 g) underwent a coarctation repair with a polydioxanone banding. Seven had a trabecular and four a perimembranous VSD. The mean size of the VSD was 5 +/- 0.7 mm (range 4 to 7 mm). The systolic pulmonary pressure was >80% of the aortic pressure in all. The pulmonary band was tightened until the systolic pulmonary pressure fell below 50% of the aortic pressure.

RESULTS

There were no hospital deaths. The reabsorption of the banding was complete after 5.7 months in all patients (3 to 6.5 months). The VSD closed completely in four infants and partially in six, in whom the pulmonary artery pressure was normal without evidence for significant left-to-right shunt. One patient with a large trabecular VSD underwent surgical closure of his defect after four months. Finally, a subsequent open-heart surgery could be avoided in 91% (10/11) of patients.

CONCLUSIONS

Provided the VSD belongs to types prone to close spontaneously, this policy may reduce the number of surgical procedures per infant as well as in-hospital mortality and morbidity rates. It should be proposed as an alternative to more complex procedures.

摘要

目的

我们提出一种新策略,即采用缩窄修复术联合聚二氧六环酮可吸收性肺动脉束带术,以降低手术风险,并避免患有主动脉缩窄的婴儿进行后续手术。

背景

对于合并室间隔缺损(VSD)的主动脉缩窄,手术治疗的替代方案是一期修复术与缩窄修复术(伴或不伴肺动脉束带术)。

方法

11例婴儿(平均体重2560±1750g,范围1320至3800g)接受了聚二氧六环酮束带缩窄修复术。7例有小梁型室间隔缺损,4例有膜周型室间隔缺损。室间隔缺损的平均大小为5±0.7mm(范围4至7mm)。所有患儿的收缩期肺动脉压均>主动脉压的80%。收紧肺动脉束带,直到收缩期肺动脉压降至主动脉压的50%以下。

结果

无住院死亡病例。所有患者的束带在5.7个月(3至6.5个月)后完全吸收。4例婴儿的室间隔缺损完全闭合,6例部分闭合,这些患儿的肺动脉压正常,无明显左向右分流证据。1例有大型小梁型室间隔缺损的患儿在4个月后接受了缺损的手术闭合。最后,91%(10/11)的患者可避免后续的心脏直视手术。

结论

如果室间隔缺损属于易于自发闭合的类型,该策略可能会减少每个婴儿的手术次数以及住院死亡率和发病率。应将其作为更复杂手术的替代方案。

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