Pembrey L, Newell M L, Tovo P A
University of Turin, Department of Pediatrics, Division of Immunology and Infectious Diseases, Regina Margherita Children's Hospital, Piazza Polonia 94, I-10126 Turin, Italy.
Eur J Pediatr. 1999 Oct;158(10):842-6. doi: 10.1007/s004310051219.
A postal survey of 31 European centres was conducted to document current practices regarding screening and management of hepatitis C virus (HCV)-infected pregnant women and their children. Antenatal HCV prevalence was low. Universal antenatal screening programmes were in place in ten centres, selective screening occurred in ten other centres, two did not specify the type of policy, and there was no screening programme in nine centres. Numbers of HCV-infected children were low. Breastfeeding was recommended for infants of infected mothers in ten centres, discouraged in ten centres, in three centres women were merely informed of the risks, and there were no guidelines in eight centres. Polymerase chain reaction was available in all centres. In 17 centres children born to HCV-infected women were seen every 3 months for at least the 1st year.
The optimum antenatal hepatitis C virus screening approach and the appropriateness of breastfeeding recommendations are unclear and this survey highlights the lack of uniformity in current practice.
对31个欧洲中心进行了一项邮政调查，以记录当前关于丙型肝炎病毒（HCV）感染孕妇及其子女的筛查和管理做法。产前HCV流行率较低。10个中心实施了普遍产前筛查计划，另外10个中心进行选择性筛查，2个中心未具体说明政策类型，9个中心没有筛查计划。HCV感染儿童数量较少。10个中心建议感染母亲的婴儿进行母乳喂养，10个中心不鼓励母乳喂养，3个中心仅告知女性相关风险，8个中心没有相关指南。所有中心均有聚合酶链反应检测。在17个中心，HCV感染女性所生儿童在至少第一年每3个月接受一次检查。
最佳产前丙型肝炎病毒筛查方法以及母乳喂养建议的适宜性尚不清楚，本次调查突出了当前做法缺乏一致性的问题。
