对患有其他冠心病危险因素的患者进行高胆固醇血症筛查。

Screening for hypercholesterolaemia in patients with other risk factors for coronary heart disease.

作者信息

Lee G H, Su D H, Su D H, Fong A C, Chow Y H

机构信息

Faculty of Medicine, National University of Singapore, Singapore.

出版信息

Singapore Med J. 1999 Jun;40(6):397-401.

PMID:10489507

Abstract

OBJECTIVE

To determine the prevalence of hypercholesterolaemia in individuals with other major risk factors of coronary heart disease and markers of hypercholesterolaemia.

METHODS

A community-based cross-sectional study on a random sample of 261 persons aged between 35 and 69 years residing in the flatted housing estate of West Coast, Singapore, was conducted in 1997. A questionnaire, together with a medical examination and investigation involving the use of Reflotron machine, were used to collect the information required.

RESULTS

43.2% of the population had at least 1 major risk factor, with 18.1% being smokers, 18.1% with hypertension, 6.5% with diabetes mellitus, 5.1% being obese, and 5.0% with a family history of coronary heart disease. Higher percentages of individuals with hypercholesterolaemia were found when each risk factor was present. 9.5% had 2 or more risk factors, of which, 21.1% had high cholesterol levels. A high prevalence of hypercholesterolaemia that was statistically significant was found amongst subjects with corneal arcus below the age of 60.

CONCLUSIONS

The risk factors of coronary heart disease remain prevalent in our population. We recommend screening for serum cholesterol only in those with at least 2 major risk factors of coronary heart disease in the general population between 35 and 69 years of age.

摘要

目的

确定患有冠心病其他主要危险因素及高胆固醇血症标志物的个体中高胆固醇血症的患病率。

方法

1997年对居住在新加坡西海岸公寓小区的261名年龄在35至69岁之间的随机样本进行了一项基于社区的横断面研究。使用问卷以及包括使用Reflotron机器在内的医学检查和调查来收集所需信息。

结果

43.2%的人群至少有1种主要危险因素，其中吸烟者占18.1%，高血压患者占18.1%，糖尿病患者占6.5%，肥胖者占5.1%，有冠心病家族史者占5.0%。当每种危险因素存在时，发现高胆固醇血症患者的比例更高。9.5%的人有2种或更多危险因素，其中21.1%的人胆固醇水平高。在60岁以下有角膜弓的受试者中发现高胆固醇血症的患病率很高，且具有统计学意义。