Chung I H, Kim C S, Seo J H, Chung B Y
Biochemicals Research Center, Korea Institute of Science and Technology, Seoul.
Arch Pharm Res. 1999 Aug;22(4):391-7. doi: 10.1007/BF02979063.
The quaternary ammonium cephalosporin derivatives were prepared with various pyridines substituted at the 3 or/and 4 position. Their in vitro antibacterial activities were determined and substituent effect on pyridine nucleus was studied. Preparation of substituted pyridines are also described.