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[Epley法与Semont法治疗良性阵发性位置性眩晕的荟萃分析]

[Meta-analysis of the treatment of benign paroxysmal positional vertigo by Epley and Semont maneuvers].

作者信息

López-Escámez J, González-Sánchez M, Salinero J

机构信息

Servicio de ORL, Hospital Universitario Virgen de las Nieves, Granada, España.

出版信息

Acta Otorrinolaringol Esp. 1999 Jun-Jul;50(5):366-70.

Abstract

OBJECTIVE

To determine the effectiveness of Epley and Semont maneuvers in treating benign paroxysmal positional vertigo (BPPV).

DESIGN

Systematic search of the medical literature to identify studies that used Epley or Semont maneuvers in randomized controlled trials to treat BPP'V. Studies were examined blind and the results of the studies with a satisfactory methodological quality were pooled.

SUBJECTS

Four studies of adults with a clinical diagnosis of BPPV.

MAIN OUTCOME MEASURES

Subjective sensation of vertigo 7 and 30 days after treatment, positional objective nystagmus and vertigo evoked by the Dix-Hallpike test (DHT) 7 and 30 days after treatment.

RESULTS

Seventy percent of Epley maneuver-treated adults and 95% of placebo-treated adults reported new episodes of vertigo at 7 days. Moreover, 100% had a positive DHT (odds ratio 0.11; p = 0. 0072). However, 30 days after treatment 59% of treated adults (Epley or Semont) remained asymptomatic and 89% were unresponsive to DHT. Subjective remission of BPPV occurred in 47% of placebo-treated subjects, but only 27% had a negative DHT (odds ratio 0.05 for Epley maneuver-treated evaluated by DHT).

CONCLUSIONS

The Epley canalith repositioning procedure or Semont maneuver had a significantly higher efficacy rate in patients with BPPV than placebo procedures, but results must be evaluated at 30 days by DHT. DHT is an easy, low-cost and effective method for assessing the outcome of treatment in patients with BPPV.

摘要

目的

确定Epley法和Semont法治疗良性阵发性位置性眩晕(BPPV)的有效性。

设计

系统检索医学文献,以识别在随机对照试验中使用Epley法或Semont法治疗BPPV的研究。对研究进行盲法审查,并汇总方法学质量令人满意的研究结果。

研究对象

四项针对临床诊断为BPPV的成年人的研究。

主要观察指标

治疗后7天和30天的眩晕主观感受、位置性客观眼震以及Dix-Hallpike试验(DHT)诱发的眩晕。

结果

接受Epley法治疗的成年人中有70%以及接受安慰剂治疗的成年人中有95%在7天时报告有新的眩晕发作。此外,100%的患者DHT结果为阳性(优势比0.11;p = 0.0072)。然而,治疗30天后,59%接受治疗的成年人(Epley法或Semont法)无症状,89%对DHT无反应。安慰剂治疗的受试者中47%出现BPPV主观缓解,但只有27%的患者DHT结果为阴性(通过DHT评估,Epley法治疗的优势比为0.05)。

结论

Epley管石复位法或Semont法治疗BPPV患者的有效率显著高于安慰剂治疗,但必须在30天时通过DHT评估结果。DHT是评估BPPV患者治疗效果的一种简便、低成本且有效的方法。

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