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一项基于人群的新南威尔士州儿童脑结核研究。

A population-based study of children with cerebral tuberculosis in New South Wales.

作者信息

Arestis N, Tham Y J, McIntyre P B, Isaacs D, Palasanthiran P, Ferguson J K, Wilkinson I, Dawson D, Christensen A J

机构信息

Royal Alexandra Hospital for Children, Sydney, NSW.

出版信息

Med J Aust. 1999 Aug 16;171(4):197-200. doi: 10.5694/j.1326-5377.1999.tb123597.x.

DOI:10.5694/j.1326-5377.1999.tb123597.x
PMID:10494236
Abstract

OBJECTIVE

To determine the incidence of childhood cerebral tuberculosis (tuberculous meningitis [TBM] and tuberculoma) in a defined population.

DESIGN

Retrospective, population-based study.

SETTING AND PARTICIPANTS

All resident children aged up to 14 years in New South Wales diagnosed with cerebral tuberculosis, from 1982 to 1996.

MAIN OUTCOME MEASURE

Population-based incidence of childhood TBM.

RESULTS

10 children with TBM and one with tuberculoma were identified in the 15 years. The incidence of TBM was 0.053 (95% CI, 0.025-0.097) per 100,000. Eight of the 10 TBM patients were born in Australia and five were of white European origin. Only one had been vaccinated with BCG vaccine. Three of the children died.

CONCLUSIONS

The incidence of childhood TBM in New South Wales is low, and comparable with that in other First World countries.

摘要

目的

确定特定人群中儿童脑结核(结核性脑膜炎[TBM]和结核瘤)的发病率。

设计

基于人群的回顾性研究。

地点和参与者

1982年至1996年在新南威尔士州诊断为脑结核的所有14岁及以下常住儿童。

主要观察指标

基于人群的儿童TBM发病率。

结果

在这15年中,确定了10例TBM患儿和1例结核瘤患儿。TBM的发病率为每10万人0.053(95%可信区间,0.025 - 0.097)。10例TBM患者中有8例出生在澳大利亚,5例为欧洲白人血统。只有1例接种过卡介苗。3名儿童死亡。

结论

新南威尔士州儿童TBM的发病率较低,与其他第一世界国家相当。

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