[鹿特丹手术室工作人员中 IgE 介导的天然橡胶乳胶过敏患病率]

[Prevalence of IgE-mediated allergy to natural rubber latex in operation room personnel of Rotterdam].

作者信息

Bijl A M, de Jong N W, Mulder P G, Gerth van Wijk R, de Groot H

机构信息

Afd. Allergologie, Academisch Ziekenhuis Rotterdam-Dijkzigt.

出版信息

Ned Tijdschr Geneeskd. 1999 Aug 28;143(35):1780-4.

PMID:10494330

Abstract

OBJECTIVE

To determine the prevalence of IgE-mediated latex allergy in workers in an operation room (OR) complex.

DESIGN

Descriptive.

METHOD

Regular OR staff members of Rotterdam University Hospital were tested in May-July 1998 for latex allergy and cross-reacting allergens. Questionnaires, serologic testing and skin prick tests with different extracts were used.

RESULTS

The study group comprised 163 persons (response: 70%), 30 men and 133 women, with a mean age of 38 years (range: 18-60). Twenty-three persons (14.1%) had specific IgE antibodies against latex. Persons with an atopic constitution ran an increased risk of latex sensitization (odds ratio: 4.3; 95% confidence interval: 1.6-11.4). Of these 23 persons, 16 showed symptoms of urticaria, angio-oedema, rhinoconjunctivitis and/or dyspnoea.

CONCLUSION

IgE-mediated allergy to natural rubber latex was prevalent in 23/163 (14.1%) of the OR personnel.

摘要

目的

确定手术室综合大楼工作人员中IgE介导的乳胶过敏的患病率。

设计

描述性研究。

方法

1998年5月至7月，对鹿特丹大学医院的常规手术室工作人员进行乳胶过敏和交叉反应性过敏原检测。采用问卷调查、血清学检测以及不同提取物的皮肤点刺试验。

结果

研究组包括163人（应答率：70%），其中30名男性和133名女性，平均年龄38岁（范围：18 - 60岁）。23人（14.1%）有针对乳胶的特异性IgE抗体。特应性体质者发生乳胶致敏的风险增加（优势比：4.3；95%置信区间：1.6 - 11.4）。在这23人中，16人出现荨麻疹、血管性水肿、鼻结膜炎和/或呼吸困难症状。